Abstract: The connotation of scientific spirit is seeking for truth, innovating, suspecting, and insisting, whereas the connotation of humanistic spirit is seeking for being good and people-oriented, aiming to all-around development of people. In the past, scientific spirit has always been separated from humanistic spirit in higher education. Facing the challenges of Knowledge Economy, Globalization, and the Sustainable Development that our time endows us with, higher education is in strait. The integration of the scientific spirit and the humanistic spirit should become trendy. The possibility of the integration of those two spirits lies in that they have the same origin. This paper points out that the feasible way to integrate the two spirits is to take reform in all the aspects of higher education, including the concepts, the modes, the curriculum, and the systems, ect.