Abstract: Research on the number of Internet users can support reference to study standards of consumption in residents, as well as socio-economic development and level of informatization, science and technology development level. The number of Internet users forecast can provide aid decision making for information and communications industry, at the same time support a basis to economic development. Make use of matlab that powerful computing ability and a high degree of expandability. It collected data samples and divide data. As the study of non-linear features, it set up a prediction model use of artificial neural network theory of radial basis function RBF neutral network, and to verify the model based on matlab. This predicts have good results. The result can provide reference for other fields.