Abstract: It is significant for improving the efficiency of emergency logistics to establish quick， agile and efficient response mechanism when we are copying with a crisis. The paper established the defense system， response procedures and response mechanism of emergency logistics to imitate the characteristics of the immune system， the theory of immune response and response mechanism. It provided a new idea for found a new-type emergency logistics response system. They are of vital importance for the improvement of the security of emergency system， normalization of the process of emergency response and the enhancement of the sensibility of emergency response.